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Histamine intolerance test

The amino acid histidine is one of the tissue hormones.

If histamine degradation is suboptimal, especially if large amounts of histamine accumulate and the histamine-degrading enzymes such as diamine oxidase (DAO) and histamine N-methyltransferase (HNMT) are insufficiently active in the liver, an excessive amount of histamine can develop in the body. Histamine intolerance (HIT) is therefore a sign of an imbalance between the amount of histamine produced and its breakdown. It is not only foods with a high histamine content that influence the amount of histamine in the body: an excessive number of histamine-producing bacteria in the gut, allergies or medication that inhibits the breakdown of histamine can also have an impact.

The symptoms that typically occur with histaminosis can be varied. Excessive histamine levels can lead to circulatory problems, headaches, shortness of breath, allergy-like symptoms and skin rashes. However, gastrointestinal complaints such as stomach pain, heartburn, cramps, flatulence and diarrhoea are also possible. This urine test is used to determine histamine and its metabolites in urine.

In the intestine, the main degradation of histamine is carried out by the enzyme diamine oxidase (DAO), which produces imidazole acetaldehyde and imidazole acid. As a second intracellular degradation pathway, histamine is converted by N-methyltransferase into the products N-methylhistamine, N-methylimidazoleacetaldehyde and N-methylimidazoleacetic acid. The relationships between N-methylhistamine and histamine as well as imidazoleacetic acid and histamine provide insights into the function of DAO and the activity of HNMT.

The following parameters are analysed:

  • Histamine
  • imidazoleacetic acid
  • Imidazoleacetic acid/histamine ratio
  • N-methylhistamine
  • N-methylimidazoleacetic acid
  • Ratio N-methylhistamine/histamine Diagnosis

The results form the basis for a customised therapy, which should only be carried out after consultation with a doctor or therapist.

The test kit contains

  • 1 instruction for sample collection
  • 1 urine beaker
  • 1 yellow urine tube (urine monovette)
  • 1 yellow tip
  • 1 shipping container for urine monovette
  • 1 envelope

How does the ordering process work?

After placing your order, you will be sent the desired test pack with detailed instructions. You put your sample in a sample container, send it in a prepared envelope to Medivere's partner laboratory GANZIMMUN Diagnostics GmbH and receive a report with the evaluation of your profile after 5-7 days.

Only for Germany and Austria

We would like to point out that these tests and the shipping procedures are optimised and pre-paid for Germany and Austria. Orders from further afield are problematic because the perishable biological samples may only be in transit for a limited time (maximum 4 days). Customers from Switzerland or other EU countries can of course try it at their own risk, but if the test fails, we decline any responsibility or reimbursement. You can find more information on this from the manufacturer!

Only for Germany and Austria

  • We would like to point out that these tests and the shipping processes are optimized for Germany and Austria and are prepaid.
  • Samples must be delivered to the German laboratory within 4 days. This cannot be guaranteed for samples shipped from other countries!
  • Orders from countries other than Germany and Austria are therefore at your own risk. In this case, we only accept the payment method "Prepayment (directly to us)", as customers cannot then cancel the purchase, e.g., because the sample arrived at the laboratory unusable through their own fault. Purchases made with any other payment methods that customers could unlawfully reverse will be immediately canceled and refunded.
  • You can find more information about this from the manufacturer!
Product Type: Medizinprodukt
Test-Art: Urintest
Sample findings

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Test instructions

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Sensible nutritional supplements after a sensible analysis!

Vitamins and minerals can best be dosed if you know exactly what your supply or deficiency of a nutrient is. Our customers can take this into their own hands with the test kits from Medivere! Test kits that we have in stock can be ordered from us. For test kits that are not in stock, we refer you directly to the manufacturer, who will be happy to send them to you without going through us*. You are then welcome to send us your test results and we will be happy to advise you on which products you need. For more comprehensive health advice, we are also happy to refer you to experienced alternative practitioners and osteopaths with whom we work**. You will then also receive a 5% voucher for your next purchase from us (our favourable graduated prices with a 5-10% volume discount naturally apply in addition to the voucher).
*The green button will then say "to product" instead of "shopping basket". We receive a small payment from Medivere for this advertising. **They are also happy to accept you personally as a client if you are in Dresden or Bautzen. If not, tele-appointments may also be possible.

Manufacturer's address: medivere GmbH, Hans-Böckler-Straße 109, 55128 Mainz, Germany.
E-Mail:medizinproduktesicherheit@medivere.de

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