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Berberin 500 mg, 60 capsules

High-purity extract from the roots of Berberis aristata

The important bioactive substance berberine is found in the roots, stem, bark and berries of the Berberis plant. The species used by Vitals is also known as Indian barberry or tree turmeric.
Plants containing berberine have been used for thousands of years in India, China, Japan and numerous other countries. Since the 1950s berberine has also been used as an isolated substance and offered as a dietary supplement. Scientific interest has grown considerably over the past two decades, and there are now around 200 published articles on berberine each year.

Absorption of berberine

Part of the berberine remains in the gastrointestinal tract. It leaves beneficial bacteria undisturbed, making it ideal to take before or together with a probiotic. After absorption by the intestinal mucosa, some is pumped back into the intestinal lumen and metabolised in the intestinal wall or in the liver. Therefore it is understandable why plasma levels of berberine remain low. However, there are also studies showing that berberine and its metabolites are rapidly taken up by organs such as the liver, kidneys, muscles, lungs, brain, heart, pancreas and adipose tissue. In most of the tissues analysed, berberine levels were found to be many times higher than blood plasma levels.

Effects of berberine

A central mechanism of action of berberine is that it promotes the activity of AMPK (adenosine monophosphate-activated protein kinase), known as the "metabolic master switch". This enzyme is involved in glucose and lipid metabolism by supporting cellular uptake and oxidation of glucose and fatty acids. As a result, it influences blood sugar and cholesterol levels.

Active constituents

Active constituents* per daily portion per 1 capsule
Berberine-HCl 500 mg

* No reference intake specified according to the EU Food Information Regulation

Ingredients

Berberine hydrochloride (berberine, extracted from Berberis aristata, root), rice starch (Oryza sativa), vegetable capsule (pullulan, from fermented cassava starch), sunflower oil (Helianthus annuus).

Recommended intake

Take 1–2 capsules per day with water at a meal.

Storage instructions

Store in a cool, dry place protected from light (do not refrigerate).

Legal notice

Do not exceed the recommended daily intake. Food supplements are not a substitute for a balanced and varied diet and a healthy lifestyle. Keep out of reach of young children.

Application: Anti-ageing, Blood sugar, Heart & Blood Vessels
Dosage form: In vegan capsules.
Plants: barberry
Quality: Free from magnesium stearate, Gluten-free, Lactose-free, Vegan
Product type: Dietary supplements
Name of the foodstuff: Dietary supplements containing plant-based ingredients

Vitals, our new brand from 2025

We are constantly on the lookout for brands that represent our ideals: highest quality, the consistent omission of unnecessary additives such as titanium dioxide or porcine gelatin, excellent value for money and absolute reliability in delivery to us and thus to our customers.
This is very difficult because such companies are extremely rare among the mass of dietary supplement manufacturers now on the market. But we have once again managed to find one with Vitals from the Netherlands!

Address of the manufacturer: Vitals Voedingssupplementen BV, Pieter Lieftinckweg 29, 1505 HX Zaandam, Netherlands. E-mail: kundendienst@vitals.eu.

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