Vitamin B6 20 mg, 100 capsules

P5P is the active form the body needs.

In all Vitals products containing vitamin B6 only the biologically active form, pyridoxal-5′-phosphate (P5P), is used, whereas pyridoxine HCl, which must first be converted in the body, is not used. The biologically active vitamin B6 in the form of pyridoxal-5′-phosphate acts as a cofactor in over 140 enzyme reactions in the body and thus fulfils various physiological functions. Almost all amino acids require one or more enzymes that depend on pyridoxal-5′-phosphate for their metabolism. P5P-dependent enzymes are also important in glycogen metabolism. Vitamin B6 therefore contributes to good energy supply and can help with fatigue.

Pyridoxal-5′-phosphate is also involved in the synthesis of haem compounds and haemoglobin and plays a role in the binding and release of oxygen in red blood cells. Haem compounds are also present in the mitochondria, which explains the influence of pyridoxal-5′-phosphate on energy levels. As pyridoxal-5′-phosphate is taken up into the brain and P5P-dependent enzymes are involved in the synthesis of neurotransmitters, it contributes to the normal functioning of the brain and nerves.

Vitamin B6 is also important for the immune system, as it is required as a coenzyme in the production of certain immunoglobulins (antibodies that fight viruses or bacteria) and cytokines (substances that activate or inhibit the immune system). It is also involved in the synthesis of cysteine as well as in the formation and metabolism of homocysteine. Vitamin B6 also has a regulatory effect on hormonal activity.

Reliable upper limit

Very high doses of vitamin B6 can occasionally cause tingling or numbness in the hands or feet. For this reason, the maximum safe upper limit for vitamin supplements for adults is set at 21 mg per day in the Netherlands. It is currently being investigated whether the occasional side effects occur only with vitamin B6 in the form of pyridoxine HCl and not, or to a lesser extent, with pyridoxal-5′-phosphate. Evidence suggests that only pyridoxine is toxic to nerve cells at high doses, whereas P5P does not appear to be. The Vitals product named “Vitamin B6 Pyridoxal-5'-Phosphate” contains a high dosage (20 mg) of this active ingredient in pure, biologically active form. The raw material is contained in a vegetable capsule made from cassava and is complemented with an excipient based on rice.

Vitamin B6

• contributes to normal protein and glycogen metabolism
• supports energy levels
• can contribute to the reduction of tiredness
• plays a role in homocysteine metabolism
• is, among other things, important for the formation of red blood cells
• has a positive influence on nervous system function
• contributes to the normal functioning of the immune system
• contributes to normal brain functions
• regulates, among other things, the activity of hormones

Nutritional information

*Reference intake according to Regulation (EU) No. 1169/2011

Ingredients

Anti-caking agent (rice fibres), vegetable capsule (pullulan, from fermented cassava starch), pyridoxal-5′-phosphate (P5P).

Recommended use

Take 1 capsule per day with water during a meal.

Caution

This food supplement is not suitable for children and adolescents up to and including 17 years of age (legally required warning for products with more than 7 mg vitamin B6 per daily dose).

Storage instructions

Store cool, dry and protected from light (do not refrigerate).

Legal notice

The recommended daily intake should not be exceeded. Food supplements are not a substitute for a balanced and varied diet and a healthy