Vitamin B6 20 mg, 100 capsules

P5P is the active form that the body needs.

All Vitals products containing vitamin B6 use exclusively the biologically active form, pyridoxal-5′-phosphate (P5P), whilst pyridoxine HCl, which must first be converted in the body, is not used. The biologically active vitamin B6 in the form of pyridoxal-5′-phosphate is involved as a cofactor in over 140 enzymatic reactions in the body and thus fulfils various physiological functions. For their metabolism, almost all amino acids require one or more enzymes that depend on pyridoxal-5′-phosphate. P5P-dependent enzymes are also important in glycogen metabolism. Vitamin B6 therefore contributes to a good energy supply and can help with fatigue.

Pyridoxal-5′-phosphate is also involved in the synthesis of haem compounds and haemoglobin and plays a role in the binding and release of oxygen in red blood cells. Haem compounds are also present in the mitochondria, which explains the influence of pyridoxal-5′-phosphate on energy levels. As pyridoxal-5′-phosphate is taken up by the brain and P5P-dependent enzymes are involved in the synthesis of neurotransmitters, it contributes to the normal functioning of the brain and nerves.

Vitamin B6 is also important for the immune system, as it is required as a coenzyme in the production of certain immunoglobulins (antibodies that fight viruses or bacteria) and cytokines (substances that activate or inhibit the immune system) . It is also involved in the synthesis of cysteine and in the formation and metabolism of homocysteine. Vitamin B6 also has a regulatory effect on hormonal activity.

Reliable upper limit

Very high doses of vitamin B6 can occasionally cause tingling or numbness in the hands or feet. For this reason, the maximum safe upper limit for vitamin supplements in adults in the Netherlands is set at 21 mg per day . Research is currently being carried out to determine whether these occasional side effects occur only with vitamin B6 in the form of pyridoxine HCl and not, or to a lesser extent, with pyridoxal-5′-phosphate. Evidence suggests that only pyridoxine is toxic to nerve cells at high doses, whilst P5P does not appear to be. The Vitals product called ‘Vitamin B6 Pyridoxal-5'-Phosphate’ contains a high dose (20 mg) of this active ingredient in its pure, biologically active form. The active ingredient is contained in a vegetable capsule made from cassava and is supplemented with a rice-based excipient.

Vitamin B6

• contributes to the normal metabolism of protein and glycogen
• supports energy levels
• may help reduce tiredness
• plays a role in homocysteine metabolism
• is important, amongst other things, for the formation of red blood cells
• has a positive effect on the function of the nervous system
• contributes to the normal functioning of the immune system
• contributes to normal brain function
• regulates, amongst other things, the activity of hormones

Nutrition declaration

*Reference value according to Regulation (EU) No 1169/2011

Ingredients

Anti-caking agent (rice fibre), vegetable capsule (pullulan, from fermented cassava starch), pyridoxal-5′-phosphate (P5P).

Recommended intake

Take 1 capsule per day with water as part of a meal.

Caution

This food supplement is not suitable for children and young people up to and including the age of 17 (statutory notice for products containing more than 7 mg of vitamin B6 per daily dose).

Storage instructions

Store in a cool, dry place away from light (not in the fridge).

Legal information

Do not exceed the recommended daily intake. Food supplements are not a substitute for a balanced and varied diet and a healthy