50+ Multivitamins, 60 tablets, for daily use

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Jeden Tag 50+ specifically for men and women over 50

As we age, the body's nutrient requirements change. Therefore the need for iron and copper decreases. For that reason Jeden Tag 50+ contains neither iron nor copper. For men and women in this age group it is important to take additional vitamin B12 and sufficient folic acid (folate) to support, among other things, mental functions and memory. Larger amounts of vitamins K2 and D3 are also important for this age group.

B vitamins in the ideal form and dosage

Jeden Tag 50+ provides 50 μg vitamin B12 in the biologically active forms methylcobalamin and adenosylcobalamin. These are qualitatively far superior to the common cheap cyanocobalamin.

It also contains 300 μg active folic acid in the best form, 5-methyltetrahydrofolate. Approximately 50% of people cannot utilise the simple folic acid found in many supplements and medicines because their metabolism cannot convert it into the active folate form the body needs. 5-MTHF is already converted and can be used without difficulty by these people.

High-dosed vitamin D3 and K2

Calcium is positioned in the right place in bone through the action of vitamin K. This is particularly important for this age group. Jeden Tag 50+ provides 45 μg K1 (phytomenadione) and at least 90 μg vitamin K2. Vitamin D is also important for the bones, but its range of effects is much broader: among other things it has positive effects on resistance, muscle function and normal cell division. Therefore one tablet contains a high dose of 35 μg vitamin D3, because vitamin D is very important and has numerous positive properties.

Supporting eye health and special additions

In addition, Jeden Tag 50+ contains vitamins A and B2 and zinc, which all contribute to the preservation of vision. The amounts of lutein, zeaxanthin and meso-zeaxanthin are also higher than in other products. Finally, the special substances Q10, alpha-lipoic acid and pterostilbene were added.

B vitamins in the best possible form and with the ideal dosage

The Jeden Tag multis contain a large quantity, but in an acceptable dosage, of B vitamins. The daily requirement, average intake amounts and their lower limits have been examined in detail. Not only the latest scientific findings and the safe upper limits are taken into account, but also the body's ability to convert the different B vitamins. Furthermore, all formulas include the biologically active forms of vitamins B2 (riboflavin-5'-phosphate), B6 (pyridoxal-5'-phosphate), B12 (methyl- and adenosylcobalamin) and folic acid (5-methyltetrahydrofolate glucosamine salt). These are the forms used by the body, and research shows they have higher bioavailability in the body.

Pyridoxal-5'-phosphate as the form of vitamin B6

Occasionally a tingling or numbness in the hands or feet can occur when very high amounts of vitamin B6 are taken. For this reason a maximum safe daily dose of 21 mg for adults applies to vitamin supplements in the Netherlands. The daily multis are well below this (maximum 4.2 mg). Only the biologically active form of vitamin B6, pyridoxal-5'-phosphate (P-5'-P), is used, instead of pyridoxine-HCl, which still needs to be converted in the body. It is currently being investigated whether the occasional side effects mentioned above occur only with vitamin B6 in the form of pyridoxine-HCl and not, or to a lesser extent, with pyridoxal-5'-phosphate. Indications suggest that only pyridoxine-HCl is neurotoxic in high doses.

Folic acid as 5-methyltetrahydrofolate

The folic acid (pteroylmonoglutamic acid) often used in supplements for reasons of stability is a synthetic form that does not occur naturally. In food it occurs as folate. Folic acid taken via supplements must be converted in the body to tetrahydrofolate and subsequently to 5-methyltetrahydrofolate (5-MTHF). Studies show that this complicated conversion process is far from optimal in a considerable number of people. Adding 5-MTHF eliminates this problem.
The Jeden Tag multis use the superior form 5-methyltetrahydrofolate bound as a glucosamine salt (under the brand name Quatrefolic®). Thanks to this binding with glucosamine salt (of plant origin) the biologically active form can be kept stable and optimal absorption is ensured. Studies show that Quatrefolic® is characterised by higher water solubility, stability and bioavailability. Moreover, 5-MTHF can cross the blood–brain barrier, unlike the “normal” (synthetic) form of folic acid.

Vitamin B12 in the form of adenosyl- and methylcobalamin

The process of absorbing vitamin B12 from food is complicated. There are also indications that the NRV (formerly RDA) of 2.5 µg per day was set too low and that the requirement in healthy adults and older people can vary and rise above 20 µg per day. To ensure the safety of vitamin B12 supplementation and to take into account the fact that absorption of B12 from foods and supplements is not always straightforward, the Jeden Tag multis contain higher doses of the biologically active forms methyl- and adenosylcobalamin.

Cyanocobalamin, an inexpensive synthetic variant of vitamin B12 that does not occur naturally and must be converted by the body into active forms, is included in many other B12 products and multivitamins. The cyanide portion of the cobalamin (B12) is separated, which then requires processing by the body. According to studies, the bioavailability of vitamin B12 as methyl- and adenosylcobalamin is higher than that of cyanocobalamin.

Plant sources rich in vitamin D

In recent years European authorities have concluded that the value for an adequate vitamin D intake from food (15 µg) should be set higher and that the maximum permissible dose (100 µg) could be increased. In the Netherlands there is still caution, and it is stated that 10 µg would be sufficient and the upper limit should be 75 µg. Strangely, the NRV (or RDA) still remains 5 µg. In the orthomolecular world, however, the importance of higher doses has been recognised for some time. Leading vitamin D experts recommend that the calcidiol level in adults should be at least 75 nmol/l. To maintain such a vitamin D level in the blood, a daily oral dose of 25–75 µg vitamin D3 is required. The Jeden Tag multis contain high amounts of vitamin D3 (cholecalciferol). In terms of raising the vitamin D level, this form is far more effective than vitamin D2 (ergocalciferol). In addition, the new Jeden Tag multis contain plant-based vitamin D3 (Vitamin D3V®). The reason for this is that it is produced from algae and not from sheep wool fat (as most other vitamin D3 products are). This makes all multis from the Jeden Tag range suitable for vegans.

Vitamin K1 and K2

The Jeden Tag multivitamins now contain a small amount of vitamin K1 and an increased amount of vitamin K2. Vitamin K1 is predominantly taken up by the liver and is mainly responsible for activating clotting factors. In contrast, vitamin K2 has higher bioavailability, is distributed much more in body tissues and therefore more effectively activates other vitamin-K-dependent enzymes such as osteocalcin and MGP. These ensure, among other things, that calcium is correctly absorbed and arrives where it belongs: in the bones.
For blood coagulation, which is essential for survival, the body uses vitamin K first. Vitamin K2 is a raw material whose price is considerably higher than that of vitamin K1. Therefore a small amount of K1 is added to the multis to ensure that this is used for the primary blood clotting function, while K2 is used for the other equally important functions.
By the way, the NRV for vitamin K that has been set is based on the amount necessary for normal blood coagulation. It is odd that the optimal dosage of vitamin K for other bodily processes dependent on vitamin K was not taken into account.

Stability of vitamin K2

It appears that vitamin K2 is a very sensitive substance. The content of this vitamin in a tablet or capsule decreases particularly quickly in combination with calcium and/or magnesium. Technically it is a real challenge to use vitamin K2 in a product with high doses of calcium and/or magnesium. Therefore Vitals uses a K2 additive under the brand name K2Vital® Delta, which is stable even in a formula with many of these minerals. A patented microencapsulation process is used to protect the fat-soluble K2 particles with two layers and thus prevent reactions with other ingredients. Vitals had the stability of K2Vital® Delta tested by an independent laboratory, and it proved to be the best product. A comparison was made with other brands of vitamin K2, especially in combination with the ingredients of the Vitals products. It was concluded that protecting K2 is essential, that the K2 content remained constant with K2Vital® Delta and that it was superior to the other K2 ingredients.

Natural calcium and magnesium from the sea

For the multis, the calcium and magnesium preparations of the Aquamin® brand, which are derived from the sea, are now used. This allows the tablets to reach significantly higher doses than the forms previously used, while the absorption of these ingredients has been proven to be good.
The magnesium (Aquamin Magnesium) comes from the seawater of the Irish Sea and studies demonstrate its good bioavailability. The raw material contains about 35% elemental magnesium as well as small amounts of other minerals and trace elements.
The calcium (Aquamin Calcium) is obtained from the red algae Lithothamnium calcareum. This type of algae absorbs minerals and trace elements from the sea and stores them. Naturally it shows a nice red or pink hue, but when it dies it becomes calcified and takes on a white or light grey colour. Only calcified red algae harvested from waters along the Icelandic coast are used. The raw material contains, besides a calcium content of 32%, also 3% magnesium and small amounts of other minerals and trace elements.
Perhaps the synergistic effect of the natural trace element profile of this calcium and magnesium explains the better uptake and the impressive studies that have been carried out with it.

Zinc in the form of amino acid chelate (bisglycinate)

For the mineral zinc, amino acid chelates (bisglycinates) are used. Each zinc particle is tightly bound (chelated) to two molecules of the amino acid glycine. Minerals in this compound form can reach the small intestine well and are very well absorbed there. Vitals makes a targeted selection of Albion Minerals' amino acid chelates, recognisable by the TRAACS® brand, which stands for “The Real Amino Acid Chelate System.” This brand was created to distinguish itself from other, possibly inferior and unstable amino acid chelates. Albion holds over 100 patents worldwide that secure the process, the science and the structure of its amino acid chelate minerals.

Unique: relatively high choline dosage

Choline has been used more or less as a standard ingredient in multivitamin preparations for some time. But almost always in small amounts (between 10 and 30 mg) because little was known about it. But that is changing more and more! In 2012 the European Commission approved three health claims for choline that apply at a dose of at least 82.5 mg. It is important for normal fat metabolism, homocysteine metabolism and liver function. In the USA an RDA of 550 mg per day was established in 2016, based on clinical studies, with the aim of determining daily requirements. Choline was also recognised by EFSA in 2016 as an essential nutrient, but no NRV has yet been set for it. The recommendation for adequate intake is 400 mg per day. This is based on average intake values in European countries and not on the American study which produced a value of 550 mg per day. The average intake among European adults ranges between 291 and 468 mg per day. There are enough reasons to include a generous dose of choline in a daily multivitamin! Jeden Tag 50+ uses choline of the brand VitaCholine®. This brand represents the highest quality and extensive research has been conducted with it.

Lutein, zeaxanthin and meso-zeaxanthin

Lutein, zeaxanthin and meso-zeaxanthin are natural carotenoids. These substances are particularly highly concentrated in the retina and the macula lutea (“yellow spot”). Lutein and zeaxanthin cannot be produced by the body itself; therefore they must be obtained from the diet. They are found, among other things, in green leafy vegetables and in fruits and vegetables of red, yellow and orange colour. Meso-zeaxanthin is present in food only in small amounts (e.g. in prawns, salmon skin and the skin and flesh of trout). It is mainly formed in the retina by conversion of lutein via an enzymatic reaction. However, it can be taken easily via supplements. Meso-zeaxanthin has only recently become known as an excellent supplement and should be preferred over lutein and zeaxanthin alone.

Nutritional properties

• Vitamins B1, B2, B3, B5, B6, B12, biotin, vitamin C, iodine and manganese support energy levels
• Vitamins B2, B3, B5, B6, B12, folate and vitamin C can help with tiredness
• Vitamins A, B6, B12, folate, vitamin C, D, selenium and zinc have a positive effect on the immune system
• Vitamins B2, C, E, selenium and zinc protect cells from oxidative damage
• Vitamins B1, B2, B3, B6, B12, biotin, vitamin C and iodine support the nervous system
• Iodine and zinc contribute to normal cognitive function
• Vitamins B1, B3, B6, B12, biotin, folate and vitamin C support mental functions (such as concentration and memory) and mood
• Vitamin B5 and folate contribute to stress resistance
• Vitamins A, B2 and zinc are good for vision
• Vitamins C, D, K and zinc are good for the bones
• Vitamin K contributes to the uptake of calcium into the bones and is necessary for normal blood clotting function
• Vitamins C, D and calcium are good for the condition of the teeth
• Biotin, selenium and zinc are good for hair health
• Vitamins A, B2, B3 and C, biotin, iodine and zinc are good for skin health
• Selenium and zinc are good for nail health
• Iodine and selenium support normal thyroid function
• Vitamin D supports muscle function
• Vitamin B1 supports normal heart function
• Choline contributes to normal homocysteine metabolism and to the maintenance of cell membrane structure and normal fat metabolism
  

Nutritional declaration

*Reference intake according to Regulation (EU) No. 1169/2011
**Declaration of vitamin E content (α-TE = Total alpha-tocopherol equivalents)
***Niacin equivalent

Active ingredients

* No reference amount specified under the Food Information Regulation (FIC)

Ingredients

Minerals (calcium, magnesium, zinc, silicon, molybdenum, selenium, boron, iodine), bulking agent (microcrystalline cellulose [cellulose gel]), vitamins (C, E, B3, D3, B5, K2, B2, B1, B6, A, K1, folate, biotin, B12), choline bitartrate, lutein, Q10, anti-caking agents (silicon dioxide, magnesium salts of fatty acids), meso-zeaxanthin, stabiliser (calcium acetate), mixed tocopherols, citrus bioflavonoid complex (Citrus sinensis), alpha-lipoic acid, lycopene (Solanum lycopersicum), pterostilbene, coating agents (hydroxypropylmethylcellulose, hydroxypropylcellulose, glycerol), zeaxanthin, beta-carotene.

Recommended intake

Take 1 tablet per day with water at a meal. This supplement is not suitable for children up to and including 10 years of age (mandatory notice for products that contain more than 20 μg vitamin D per daily dose).

Caution

Because this product contains vitamin K, it is not suitable for simultaneous use with coumarin derivatives (anticoagulants such as acenocoumarol and phenprocoumon). These medicines are also referred to as vitamin K antagonists and their effectiveness is reduced by the intake of vitamin K through food and supplements.

This supplement should only be consumed by adults, with the exception of pregnant and breastfeeding women.

Storage instructions

Store in a cool, dry, light-protected place (do not refrigerate).

Legal information

The recommended daily dose should not be exceeded. Food supplements are not a substitute for a varied and balanced diet and a healthy lifestyle. Keep out of reach of young children.