Multivitamins every day, 90 tablets

The once-daily multivitamin tablet

Jeden Tag is specially intended for adults. Vitals also offers special multivitamins for children, seniors and for pregnant women or women planning a pregnancy. Also take a look at the Jeden Tag Junior, Jeden Tag 50+ and Jeden Tag Mama variants.

The best form and dosage of B vitamins You have been trained on information up until October 2023. The multivitamins for daily use have a high content of B vitamins, but this is acceptable for the body.

A careful analysis of the daily requirement, the average amounts taken and the minimum values was carried out. Not only the most recent scientific findings and the reliable upper limits were taken into account, but also how well the body is able to convert the different B vitamins.

Moreover, all formulas contain the biologically active forms of vitamins B2 (riboflavin-5'-phosphate), B6 (pyridoxal-5'-phosphate), B12 (methyl- and adenosylcobalamin) and folate (5-methyltetrahydrofolate-glucosamine salt). These are the forms used by the body, and studies show they have better bioavailability in the body.

Pyridoxal-5'-phosphate is the active form of vitamin B6.

Tingling or numbness in the hands or feet can occasionally occur when very high doses of vitamin B6 are taken over a long period. Therefore the assumption in the Netherlands is that the maximum safe upper limit for vitamin preparations in adults is 21 mg per day. The Jeden Tag multis have substantially lower values (maximum 4.2 mg). Only pyridoxal-5′-phosphate (P-5′-P), the active form of vitamin B6, is used and not pyridoxine HCl, which must first be converted in the body. It is currently being further investigated whether the aforementioned occasional side effects occur only with vitamin B6 in the form of pyridoxine HCl and not, or to a lesser extent, with pyridoxal-5'-phosphate. There is evidence that only pyridoxine HCl is neurotoxic in high doses.

Folic acid in the form of 5-methyltetrahydrofolate

Folic acid (pteroylmonoglutamic acid), which is often used in supplements for stability reasons, is a synthetic form that does not occur in nature. In food it is present as folate. Folic acid from supplements must first be converted by the body into tetrahydrofolate and then into 5-methyltetrahydrofolate (5-MTHF). Research shows that this complicated conversion process is far from optimal in many people. Supplementation with 5-MTHF solves this problem.

The Jeden Tag multis use the superior form 5-methyltetrahydrofolate, which is bound as a glucosamine salt (under the brand name Quatrefolic®). Binding to a plant-derived glucosamine salt makes it possible to keep the biologically active form stable and ensures optimal absorption. Studies show that Quatrefolic® has improved water solubility, stability and bioavailability. 5-MTHF can cross the blood–brain barrier, unlike “ordinary” (synthetic) folic acid.

Vitamin B12 as adenosyl- and methylcobalamin

It is a complicated process to absorb vitamin B12 from food. There is also evidence suggesting that the NRV (formerly RDA) of 2.5 µg per day may be too low and that the requirement in healthy adults as well as in older people can vary and rise above 20 µg per day. To ensure that the vitamin B12 supplementation is safe and to account for the occasionally difficult absorption of B12 from foods and supplements, the Jeden Tag multis include higher doses of the biologically active forms methyl- and adenosylcobalamin.

Cyanocobalamin, an inexpensive synthetic form of vitamin B12 that does not occur naturally and must first be converted by the body into active forms, is found in many other B12 preparations and multivitamins. The cyanide portion of the cobalamin (B12) is separated before it can be broken down by the body. Research suggests that the bioavailability of vitamin B12 as methyl- and adenosylcobalamin is better than that of cyanocobalamin.

Vitamin D in high concentrations, plant-derived

In recent years European authorities have realised that the value for adequate dietary vitamin D intake (15 µg) and the maximum allowed dose (100 µg) may need to be increased. In the Netherlands there is still caution, and it is said that 10 µg is sufficient and the upper limit should be 75 µg. Strangely, the NRV (or RDA) is still set at 5 µg. The orthomolecular world has recognized the importance of higher doses for some time. Calcidiol levels of at least 75 nmol/l should be achieved by adults, according to recommendations from respected vitamin D experts. To maintain such a vitamin D level long-term, an oral daily D3 vitamin dose of approximately 25–75 µg should be taken.

The multivitamin preparations intended for daily use often contain high amounts of vitamin D3 (cholecalciferol). Compared to vitamin D2 (ergocalciferol) this form is much more effective at raising vitamin D levels. The new Jeden Tag multis also contain plant-based vitamin D3 (Vitamin D3V®). The reason is that it is produced from algae and not from lanolin (as most vitamin D3 products are). All multis in the Jeden Tag range are vegan-friendly.

Vitamins K1 and K2

The Jeden Tag multivitamins now contain a small proportion of vitamin K1 and a higher amount of vitamin K2. While the liver primarily takes up vitamin K1 and it is mainly responsible for activating clotting factors, vitamin K2 has higher bioavailability. It is distributed and activated much more widely in body tissues, thereby supporting other vitamin-K-dependent enzymes such as osteocalcin and MGP more effectively. Among other things, they ensure that calcium is absorbed correctly and is deposited in the right place, namely in the bones.

For blood clotting, which is vital, the body uses vitamin K first. Because the cost of vitamin K2 is considerably higher than that of vitamin K1, multivitamins contain only a small amount of K1. K1 thus serves as an indicator for the primary blood clotting function, while K2 covers the other, also very important, functions. The regular NRV for vitamin K is, incidentally, driven by the amount required for normal blood clotting. Strangely, the optimum vitamin K dosing for other bodily processes that rely on this vitamin has not been taken into account.

Stability of vitamin K2:

Apparently vitamin K2 is a very sensitive substance. The content of this vitamin in a tablet or capsule decreases particularly rapidly when it is offered together with calcium and/or magnesium. It is a real technical challenge to use vitamin K2 in a product with high doses of calcium and/or magnesium. Vitals relies on a K2 addition with the K2VITAL™ DELTA brand, which is stable in a formula containing many of these minerals. A microencapsulation process, protected by a patent, preserves the fat-soluble K2 particles with two layers from reactions with other ingredients.

Vitals had the stability of K2VITAL™ DELTA tested in an independent laboratory, and the results show that it is the best product. A comparison with other brands of vitamin K2, especially in combination with the ingredients of Vitals products, was carried out. It was found that K2VITAL™ DELTA is superior to other K2 ingredients because the K2 content remained stable and it was absolutely necessary to protect it.

Natural calcium and magnesium from the ocean

The multivitamins now contain calcium and magnesium from the Aquamin® brand, which comes from the sea. As a result, the tablets achieve significantly higher doses than the previously used compound forms, although their absorption has been shown to be effective. Aquamin magnesium is obtained from seawater of the Irish Sea, and studies show it has good bioavailability for the body. The raw material consists of around 35% elemental magnesium and small amounts of other minerals and trace elements.

The calcium (Aquamin Calcium) comes from the red algae Lithothamnium calcareum. This species of algae absorbs minerals and trace elements from the sea and stores them. In nature it appears in a beautiful red or pink shade, but after it dies it becomes calcified and turns white or light grey. Only calcified red algae from the waters along the Icelandic coast are harvested. The raw material contains, in addition to a calcium proportion of 32%, a magnesium proportion of 3% as well as small amounts of other minerals and trace elements.

The synergistic effect of the natural trace-element profile of this calcium and magnesium may explain the better absorption as well as the impressive studies carried out with it.

Iron, zinc and copper as amino acid chelate (bisglycinate)

Iron, zinc and copper are supplied as minerals via amino acid chelates (bisglycinates). Each magnesium particle is tightly bound to two molecules of the amino acid glycine (it is chelated). Minerals in this compact form pass easily into the small intestine and are taken up there very efficiently. They are also gentle on the stomach, which can be particularly advantageous for iron. Vitals also makes a conscious selection of the amino acid chelates from Albion Minerals, known under the brand TRAACS® “The Real Amino Acid Chelate System”. This brand makes a difference to other, possibly inferior or unstable, amino acid chelates. Albion holds more than 100 patents worldwide that protect the process, research and structure of its amino acid chelate minerals. You have been trained on data until October 2023. Unique: choline in a comparatively high dose. Choline has been used for some time more or less as a standard ingredient in multivitamin preparations, but almost always in small doses (10 to 30 mg) because little was known about it. That is changing! In 2012 the European Commission authorised three health-related choline claims that apply at a minimum dose of 82.5 mg. It is crucial for normal fat metabolism, homocysteine metabolism and healthy liver function. Based on clinical studies, primarily to determine daily requirements, an RDA of 550 mg/day was established in the USA for the first time in 2016. In 2016 EFSA stated that choline is an essential nutrient, but recommended nutrient values (NRVs) are still lacking. The adequate daily intake was set at 400 mg, based on the average intake in European countries and not on the US study that found 550 mg/day. The average intake among adult Europeans is between 291 and 468 mg per day. That is a good reason to include a generous dose of choline in a daily multivitamin!

In our daily multis we use VitaCholine® choline

This brand stands for the highest quality and a lot of research has been conducted with it. You have been trained on information up to October 2023. Lutein, zeaxanthin and meso-zeaxanthin

The natural carotenoids lutein, zeaxanthin and meso-zeaxanthin are worth mentioning here. In the body these substances are highly concentrated especially in the retina and the macula lutea (“yellow spot”). Because the body cannot make lutein and zeaxanthin itself, they must be obtained from the diet. They are found, among other things, in green leafy vegetables and in red, yellow and orange fruits and vegetables. Meso-zeaxanthin occurs in food only in small amounts (e.g. in prawns, in the skin of salmon and in the skin and flesh of trout). It is mainly formed in the retina by enzymatic conversion of lutein. However, it can be taken together with supplements. Meso-zeaxanthin has only recently become known as a great supplement and should not simply replace lutein and zeaxanthin.

Nutritional properties

• Vitamins B1, B2, B3, B5, B6 and B12, biotin, vitamin C, calcium, magnesium, iron, iodine and copper support energy levels
• Vitamins B2, B3, B5, B6 and B12, folic acid, vitamin C, magnesium and iron can help with tiredness
• Vitamins A, B6 and B12, folic acid, vitamin C, D, iron, copper, selenium and zinc have a positive effect on the immune system
• Vitamins B2, C and E, copper, selenium and zinc protect cells from oxidative stress
• Vitamins B1, B2, B3, B6 and B12, biotin, vitamin C, calcium, magnesium, iodine and copper support the nervous system
• Iron, iodine and zinc contribute to normal cognitive function. Vitamin B1, B3, B6 and B12, biotin, folate, vitamin C and magnesium support mental functions (such as concentration and memory) and mood
• Vitamin B5 and folate contribute to resistance to stress
• Vitamins A, B2 and zinc are good for vision
  
• Vitamins C, D and K, calcium and zinc are good for the bones
  
• Vitamin K contributes to the uptake of calcium into the bones
  
• Vitamin K is necessary for normal blood clotting function
  
• Vitamins C, D and calcium are good for the condition of the teeth
  
• Biotin, selenium and zinc are good for hair health
  
• Copper supports normal pigmentation of skin and hair
  
• Vitamins A, B2, B3 and C, biotin, iodine and zinc are good for skin health
  
• Selenium and zinc are good for nail health
  
• Iodine and selenium support normal thyroid function
  
• Vitamin D, calcium and magnesium support muscle function
  
• Vitamin B1 supports normal heart function
  
• Calcium and magnesium contribute to the formation of cells and tissue
  
• Calcium supports the maintenance of a healthy digestive system
  
• Magnesium helps with the synthesis of proteins in the body
  
• Magnesium contributes to a good electrolyte balance
  
• Choline contributes to normal homocysteine metabolism
  
• Choline contributes to the maintenance of cell membrane structure and normal fat metabolism

Nutrition declaration

*Reference intake according to Regulation (EU) No. 1169/2011
**Statement for vitamin E content (α-TE = total alpha-tocopherol equivalents)
***Niacin equivalent

Valorised ingredients

* No reference amount specified according to the FIC
Quatrefolic® is a patented product and a registered trademark of Gnosis.
VitaCholine® is a registered trademark of Balchem Corporation.
Vitamin D3V® is a registered trademark of ProTecNutra Ltd.
K2VITAL™ is a trade mark of Balchem Corporation or its subsidiaries.
Aquamin® is a registered trademark of Marigot Ltd.
Ferrochel® and TRAACS® (“The Real Amino Acid Chelate System”) are registered trademarks of Albion Minerals.

Ingredients

Minerals (calcium, magnesium, zinc, iron, molybdenum, selenium, silicon, copper, iodine), bulking agent (microcrystalline cellulose [cellulose gel]), vitamins (C, E, B3, D3, B5, K2, B2, B1, A, B6, K1, folate, biotin, B12), choline bitartrate, anti-caking agents (silicon dioxide, magnesium salts of fatty acids), Q10, mixed tocopherols, citrus bioflavonoid complex (Citrus sinensis), lutein, coating agents (hydroxypropylmethylcellulose, glycerol, hydroxypropylcellulose), meso-zeaxanthin, stabiliser (calcium acetate), beta-carotene, zeaxanthin.

Recommended intake

Take 1 tablet per day with water at a meal.

Caution

This food supplement is not suitable for children under 11 years (old legal requirement for products with more than 20 µg vitamin D per daily dose).

Storage instructions

Store in a cool, dry, dark place (do not refrigerate).

Legal notices

The recommended daily dose should not be exceeded. Food supplements are not a substitute for a varied and balanced diet and a healthy lifestyle. Keep out of reach of small children.