Multivitamins every day, 90 tablets

The once-daily multivitamin tablet

‘Every Day’ is designed specifically for adults. Vitals also offers special multivitamins for children, older adults, and for pregnant women or women planning a pregnancy. Take a look at the ‘Every Day Junior’, ‘Every Day 50+’ and ‘Every Day Mum’ variants too.

The best form and dosage of B vitamins You have been trained on information up to October 2023. The multivitamins for daily use have a high content of B vitamins, but this is within a range that is acceptable for the body.

A careful analysis of daily requirements, average intake levels and minimum values was carried out in this regard. This takes into account not only the latest scientific findings and reliable upper limits, but also how well the body is able to metabolise the various B vitamins.

Furthermore, all formulations contain the biologically active forms of vitamins B2 (riboflavin-5'-phosphate), B6 (pyridoxal-5'-phosphate), B12 (methyl- and adenosylcobalamin) and folic acid (5-methyltetrahydrofolate glucosamine salt). These are the forms utilised by the body, and studies show that they have better bioavailability in the body.

Pyridoxal-5'-phosphate is the active form of vitamin B6.

A tingling or numbness in the hands or feet may occasionally occur when taking very high doses of vitamin B6 over a prolonged period. For this reason, in the Netherlands it is assumed that the maximum safe upper limit for vitamin supplements for adults is 21 mg per day. The ‘Every Day Multis’ contain significantly lower levels (maximum 4.2 mg). They use exclusively pyridoxal-5′-phosphate (P-5′-P), the active form of vitamin B6, and not pyridoxine HCl, which must first be converted within the body. Further research is currently being carried out to determine whether the occasional side effects mentioned above occur only with vitamin B6 in the form of pyridoxine HCl and not, or to a lesser extent, with pyridoxal-5'-phosphate. There is evidence that only pyridoxine HCl is toxic to nerve cells at high doses.

Folic acid in the form of 5-methyltetrahydrofolate

Folic acid (pteroylmonoglutamic acid), which is often used in dietary supplements for stability reasons, is a synthetic form that does not occur naturally. In food, it is present as folate. Folic acid from dietary supplements must first be converted by the body into tetrahydrofolate and then into 5-methyltetrahydrofolate (5-MTHF) . Research findings show that this complex conversion process is far from optimal in many people. Supplementing with 5-MTHF solves this problem.

The ‘Every Day Multis’ range uses the premium form 5-methyltetrahydrofolate, which is bound as a glucosamine salt (under the brand name Quatrefolic®). The binding to plant-derived glucosamine salt enables the biologically active form to be kept stable and ensures optimal absorption. Studies show that Quatrefolic® exhibits improved water solubility, stability and bioavailability. 5-MTHF can cross the blood-brain barrier, unlike ‘ordinary’ (synthetic) folic acid.

Vitamin B12 as adenosyl- and methylcobalamin

It is a complex process to obtain vitamin B12 from food . Furthermore, there is evidence to suggest that the NRV (formerly RDA) of 2.5 µg per day may be too low and that requirements in healthy adults and older and may exceed 20 µg per day. To ensure that vitamin B12 supplementation is safe and to take account of the sometimes difficult absorption of B12 from food and dietary supplements, the ‘Everyday Multis’ contain higher doses of the biologically active forms methyl- and adenosylcobalamin.

Cyanocobalamin, a cost-effective, synthetic form of vitamin B12 that does not occur naturally and must first be converted by the body into active forms, is found in many other B12 preparations and multivitamins. In this process, the cyanide component of cobalamin (B12) is separated before it is metabolised by the body. Research suggests that the bioavailability of vitamin B12 in the form of methyl- and adenosylcobalamin is better than that of cyanocobalamin.

Vitamin D in high concentrations, of plant origin

In recent years, European government bodies have recognised that the recommended intake of vitamin D from food (15 µg) and the maximum permitted dose (100 µg) may need to be increased. In the Netherlands, there is still some reluctance, and it is claimed that 10 µg is sufficient and that the upper limit should be 75 µg. Curiously, the NRV (or RDA) is still set at 5 µg . The orthomolecular community has recognised the importance of higher doses for some time now. According to the recommendations of respected experts on vitamin D, adults should achieve calcidiol levels of at least 75 nmol/l. To maintain such vitamin D levels in the long term, one should take a daily oral dose of vitamin D3 of around 25–75 µg.

Multivitamin supplements for daily use often contain high amounts of vitamin D3 (cholecalciferol). Compared to vitamin D2 (ergocalciferol), this form is significantly more effective at raising vitamin D levels. The new ‘Every Day Multis’ also contain plant-based vitamin D3 (Vitamin D3V®). The reason is that it is produced from algae rather than sheep’s wool fat (as is the case with most vitamin D3 products). All multivitamins from the ‘Every Day’ range are vegan-friendly.

Vitamins K1 and K2

The ‘Jeden Tag’ multivitamins now contain a small amount of vitamin K1 and a higher level of vitamin K2. Whilst the liver primarily absorbs vitamin K1 and is mainly responsible for activating clotting factors, vitamin K2 has higher bioavailability. It is distributed much more widely throughout the body’s tissues and activated, thereby providing more effective support for other vitamin K-dependent enzymes such as osteocalcin and MGP. Among other things, these ensure that calcium is properly absorbed and reaches the right place, namely the bones.

For blood clotting, which is vital, the body uses vitamin K first. Because the cost of vitamin K2 is considerably higher than that of vitamin K1, multivitamins contain only a small amount of K1. K1 thus serves as an indicator of primary blood clotting function, whilst K2 covers the other, equally important functions. Incidentally, the standard NRV for vitamin K is based on the amount required for normal blood clotting. Strangely enough, the optimal vitamin K dosage for other bodily processes that rely on this vitamin has not been taken into account.

Stability of vitamin K2:

Apparently, vitamin K2 is a very sensitive substance. The content of this vitamin in a tablet or capsule decreases particularly rapidly when it is supplied together with calcium and/or magnesium. It is a real technical challenge to incorporate vitamin K2 into a product containing high doses of calcium and/or magnesium. Vitals relies on a K2 supplement under the brand name K2VITAL™ DELTA, which remains stable in a formula containing many of these minerals. A patent-protected microencapsulation process protects the fat-soluble K2 particles with two layers from reacting with other ingredients.

Vitals had the stability of K2VITAL™ DELTA tested in an independent laboratory, and the results show that it is the best product. A comparison with other brands of vitamin K2, particularly in combination with the ingredients in Vitals products, was carried out. It was found that K2VITAL™ DELTA is superior to other K2 ingredients because the K2 content remained stable and it was absolutely essential to protect it.

Natural calcium and magnesium from the ocean

The multivitamins now contain calcium and magnesium from the Aquamin® brand, which is sourced from the sea. The tablets thus provide significantly higher doses than the compound forms previously used, although the absorption of these has been proven to be effective. Aquamin magnesium is extracted from the seawater of the Irish Sea , and studies show that it has good bioavailability for the body. The raw material consists of around 35% elemental magnesium, as well as small amounts of other minerals and trace elements.

The calcium (Aquamin Calcium) is derived from the red algae Lithothamnium calcareum. This species of algae absorbs minerals and trace elements from the sea and stores them. In nature, it has a beautiful red or pink hued appearance, but after it dies, it calcifies and turns white or light grey. Only calcified red algae are harvested from the waters along the Icelandic coast. The raw material contains not only 32% calcium but also 3% magnesium, as well as small amounts of other minerals and trace elements.

It is possible that the synergistic effect of the natural trace element profile of this calcium and magnesium explains the improved absorption, as well as the impressive studies that have been carried out using it.

Iron, zinc and copper as amino acid chelates (bisglycinates)

Iron, zinc and copper are supplied as minerals in the form of amino acid chelates (bisglycinates). Each magnesium particle is firmly bound to two molecules of the amino acid glycine (it is chelated). Minerals in this compact form pass easily into the small intestine and are absorbed very efficiently there. They are also gentle on the stomach, which can be particularly beneficial in the case of iron. Vitals also makes a conscious choice of amino acid chelates from Albion Minerals, known under the brand name TRAACS® ‘The Real Amino Acid Chelate System’. This brand distinguishes them from other, potentially inferior or unstable amino acid chelates. Worldwide, Albion holds more than 100 patents protecting the process, research and structure of its amino acid chelate minerals. You have been trained on data up to October 2023. Unique: choline in a relatively high dosage. Choline has long been used, more or less as a standard ingredient, in multivitamin preparations. However, it has almost always been in low doses (10 to 30 mg), as little was known about it. But that is changing more and more! In 2012, the European Commission authorised three health claims for choline, which apply at a minimum dose of 82.5 mg. It is essential for normal fat metabolism, homocysteine metabolism and healthy liver function. Based on clinical studies, particularly those aimed at determining daily requirements, an RDA of 550 mg/day was established for the first time in the USA in 2016. The EFSA concluded in 2016 that choline is an essential nutrient, but recommended nutrient values (NRVs) are not yet available. The adequate daily intake was set at 400 mg, based on the average intake in European countries and not on the American study, which determined 550 mg/day. The average intake among European adults lies between 291 and 468 mg per day. That’s a good reason to include a generous dose of choline in a daily multivitamin supplement!

In our daily multivitamins, we rely on VitaCholine® choline

This brand stands for the highest quality, and a great deal of research has been carried out on it. You have been trained on information up to October 2023. Lutein, zeaxanthin and meso-zeaxanthin

The natural carotenoids lutein, zeaxanthin and meso-zeaxanthin are worth mentioning here. In the body, these substances are found in high concentrations primarily in the retina and the macula lutea (‘yellow spot’). As the body cannot produce lutein and zeaxanthin, they must be obtained through the diet. They are found, amongst other things, in green leafy vegetables as well as in red, yellow and orange fruit and vegetables. Meso-zeaxanthin occurs in the diet only in small (e.g. in prawns, salmon skin, and the skin and flesh of trout). It is mainly produced in the retina through the enzymatic conversion of lutein. However, it can be easily taken in conjunction with dietary supplements. Meso-zeaxanthin has only recently been recognised as an excellent supplement and should replace lutein and zeaxanthin on their own.

Nutritional properties

• Vitamins B1, B2, B3, B5, B6 and B12, biotin, vitamin C, calcium, magnesium, iron, iodine and copper support energy levels
• Vitamins B2, B3, B5, B6 and B12, folic acid, vitamin C, magnesium and iron can help with tiredness
• Vitamins A, B6 and B12, folic acid, vitamins C and D, iron, copper, selenium and zinc have a positive effect on the immune system
• Vitamins B2, C and E, copper, selenium and zinc protect cells from oxidative stress
• Vitamins B1, B2, B3, B6 and B12, biotin, vitamin C, calcium, magnesium, iodine and copper support the nervous system
• Iron, iodine and zinc contribute to normal cognitive function. Vitamins B1, B3, B6 and B12, biotin, folate, vitamin C and magnesium support mental functions (such as concentration and memory) and mood
• Vitamin B5 and folate help build resilience to stress
• Vitamins A, B2 and zinc are good for eyesight
  
• Vitamins C, D and K, calcium and zinc are good for the bones
  
• Vitamin K helps the body absorb calcium into the bones
  
• Vitamin K is necessary for the normal functioning of the blood clotting system
  
• Vitamins C and D and calcium are good for dental health
  
• Biotin, selenium and zinc are good for hair health
  
• Copper supports normal pigmentation of the skin and hair
  
• Vitamins A, B2, B3 and C, biotin, iodine and zinc are good for skin health
  
• Selenium and zinc are good for nail health
  
• Iodine and selenium support the normal functioning of the thyroid gland
  
• Vitamin D, calcium and magnesium support the function of the muscles
  
• Vitamin B1 supports the normal function of the heart
  
• Calcium and magnesium contribute to the formation of cells and tissues
  
• Calcium helps maintain a healthy digestive system
  
• Magnesium helps build proteins in the body
  
• Magnesium contributes to a healthy electrolyte balance
  
• Choline contributes to normal homocysteine metabolism
  
• Choline helps maintain the structure of cell membranes and normal fat metabolism

Nutrition declaration

*Reference value according to Regulation (EU) No 1169/2011
**Information on vitamin E content (α-TE = total alpha-tocopherol equivalents)
***Niacin equivalent

Key ingredients

* No reference amount specified under the Food Information Regulation (LMIV)
Quatrefolic® is a patented product and a registered trademark of Gnosis.
VitaCholine® is a registered trademark of Balchem Corporation.
Vitamin D3V® is a registered trademark of ProTecNutra Ltd.
K2VITAL™ is a trade mark of Balchem Corporation or its subsidiaries.
Aquamin® is a registered trademark of Marigot Ltd.
Ferrochel® and TRAACS® (“The Real Amino Acid Chelate System”) are registered trademarks of Albion Minerals.

Ingredients

Minerals (calcium, magnesium, zinc, iron, molybdenum, selenium, silicon, copper, iodine), bulking agent (microcrystalline cellulose [cellulose gel]), vitamins (C, E, B3, D3, B5, K2, B2, B1, A, B6, K1, folate, biotin, B12), choline bitartrate, anti-caking agent (silicon dioxide, magnesium salts of fatty acids), CoQ10, mixed tocopherols, citrus bioflavonoid complex (Citrus sinensis), lutein, coating agents (hydroxypropyl methylcellulose, glycerol, hydroxypropyl cellulose), meso-zeaxanthin, stabiliser (calcium acetate), beta-carotene, zeaxanthin.

Recommended intake

Take 1 tablet per day with water at mealtimes.

Caution

This food supplement is not suitable for children under 11 years of age (statutory warning for products containing more than 20 µg of vitamin D per daily dose).

Storage instructions

Store in a cool, dry place away from light (not in the fridge).

Legal information

Do not exceed the recommended daily intake. Food supplements are not a substitute for a balanced and varied diet and a healthy lifestyle. Keep out of the reach of young children.